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. 2021 Oct 11;38(11):1025–1037. doi: 10.1007/s40266-021-00898-8

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/.

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Fig. 1 — Identification of ‘severe’ DDIs using BNF 77 and Stockley’s Drug Interactions. Red DDIs: a life-threatening or contraindicated combination; orange DDIs: dosage adjustment or close monitoring is needed; blue DDIs: give guidance about possible adverse effects and/or consider some monitoring; green DDIs: no interactions or no interaction of clinical significance. BNF British National Formulary, DDI drug-drug interaction