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. 2021 Nov 15;12:6602. doi: 10.1038/s41467-021-26910-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Quantitative real-time PCR analysis of the transcript levels of the MHC class I components upon SARS-CoV-2 infection (moi 3) or poly(I:C) transfection (200 ng) in Calu-3 cells. The results are from three independent experiments. b Gene expression of the transactivator and transcription factors of the MHC class I pathway upon SARS-CoV-2 infection (moi 3) or poly(I:C) transfection (200 ng) in Calu-3 cells analyzed by quantitative real-time PCR. The results are from three independent experiments. c Surface expression of MHC class I upon SARS-CoV-2, ZIKV, and TULV infection with indicated moi for 48 h in Caco-2 cells. Stimulation with IFNγ (100 U/ml) for 48 h was used as a positive control. The FACS gating strategies are provided in Supplementary Fig. 4.