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. Author manuscript; available in PMC: 2021 Nov 16.
Published in final edited form as: ACS Biomater Sci Eng. 2019 Mar 27;5(4):1956–1966. doi: 10.1021/acsbiomaterials.9b00007

Figure 2.

Figure 2.

Mineralized microspheres enhance biochemical and mechanical markers of osteogenic differentiation. (A) Gross morphology of hydrogels lacking microspheres (blank) or containing PLG microspheres (μS) or mineralized PLG microspheres (MμS). Scale bar represents 5 mm. (B) DNA, (C) calcium, and (D) collagen content over 4 weeks in culture. (E) Picrosirius red staining. Scale bar represents 100 μm. (F) Storage and (G) loss moduli over 4 weeks in culture (n = 4–6 replicates for all measurements).