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. 2021 Sep 30;118(42):e2113401118. doi: 10.1073/pnas.2113401118

Table 2.

Association between lithium use and COVID-19 susceptibility

Study cohort Lithium (n/N) Control group (n/N) Relative risk 95% CI
University of Pennsylvania Health System 33/435 46/435 0.71 [0.46–1.09]
Mount Sinai Medical Center 10/150 22/150 0.45 [0.22–0.92]
University of Iowa Health Care 50/670 120/670 0.42 [0.31–0.57]
Metaanalysis 0.51 [0.35–0.74]

Metaanalysis statistics: Test for random effect, z = −3.47, P = 0.005; test for heterogeneity, df = 2, P = 0.12, I2 = 51.6%. N = Total number of patients in the cohort; n = number in group with outcome.