TABLE 3.
Statistical analysis and comparison of side effects at each visit between the niacinamide group and cream base group
| VARIABLE | NIACINAMIDE | CREAM BASE | P-VALUE |
|---|---|---|---|
| Week 2 | |||
| Itching | 4 (21%) | 4 (21%) | 1 |
| Burning | 5 (26%) | 5 (26%) | 1 |
| Crusting | 4 (21%) | 3 (16%) | 1 |
| Greasy skin | 7 (37%) | 6 (32%) | 0.73 |
| Dermatitis | 6 (31%) | 6 (31%) | 1 |
| Week 4 | |||
| Itching | 3 (16%) | 3 (16%) | 1 |
| Burning | 1 (5%) | 2 (10%) | 1 |
| Crusting | 5 (26%) | 6 (32%) | 0.721 |
| Greasy skin | 8 (42%) | 8 (42%) | 1 |
| Dermatitis | 0 (0%) | 0 (0%) | - |
| Week 6 | |||
| Itching | 2 (11%) | 1 (5%) | 1 |
| Burning | 2 (11%) | 0 (0%) | 0.49 |
| Crusting | 5 (28%) | 4 (22%) | 1 |
| Greasy skin | 10 (56%) | 10 (56%) | 1 |
| Dermatitis | 2 (11%) | 1 (6%) | 1 |
| Week 8 | |||
| Itching | 1 (6%) | 2 (11%) | 1 |
| Burning | 1 (6%) | 1 (6%) | 1 |
| Crusting | 2 (11%) | 0 (0%) | 0.49 |
| Greasy skin | 7 (41%) | 5 (29%) | 0.47 |
| Dermatitis | 1 (6%) | 0 (0%) | 1 |
| Week 10 | |||
| Itching | 2 (12%) | 2 (12%) | 1 |
| Burning | 0 (0%) | 0 (0%) | 0 |
| Crusting | 1 (6%) | 0 (0%) | 1 |
| Greasy skin | 8 (47%) | 8 (47%) | 1 |
| Dermatitis | 0 (0%) | 0 (0%) | - |
| Week 12 | |||
| Itching | 0 (0%) | 0 (0%) | - |
| Burning | 0 (0%) | 0 (0%) | - |
| Crusting | 0 (0%) | 0 (0%) | - |
| Greasy skin | 5 (29%) | 5 (29%) | 1 |
| Dermatitis | 1 (6%) | 2 (11%) | 1 |