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. 2021 Oct 21;7(11):2987–2998. doi: 10.1021/acsinfecdis.1c00132

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© 2021 The Authors. Published by American Chemical Society

Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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Dose-dependent inhibition of AbIspC and KpIspC. IC₅₀ values for AbIspC were determined using (A) fosmidomycin or (B) FR900098. IC₅₀ values for KpIspC were also determined using (C) fosmidomycin or (D) FR900098. The R² value for each plot is indicated. IC₅₀ values were obtained using GraphPad Prism 5.0. Assays were performed in duplicate. The error bars indicate the standard deviation for each data point.