TABLE 1.
Antimicrobial activity of DoC against streptococcal species
| Strain | MIC90 (mg/ml)a |
|---|---|
| S. pneumoniae ATCC BAA-255 | 0.25 |
| S. australis ATCC 700641 | >1 |
| S. cristatus | >0.5 |
| S. infantis ATCC 700779 | >0.5 |
| S. intermedius ATCC 27335 | >0.5 |
| S. intestinalis ATCC 43492 | >1 |
| S. oligofermentus CDC SS-1725 | >1 |
| S. parasanguinis ATCC 15912 | >0.5 |
| S. peroris ATCC 700780 | >0.5 |
| S. pseudopneumoniae ATCC BAA-960 | 0.5 |
| S. salivarius ATCC 7073 | 0.5 |
| S. sanguinis ATCC 10556 | >1 |
| S. sinensis CDC SS-1726 | >0.5 |
| Dolosigranulum pigrum | >0.5 |
| S. sobrinus ATCC 33478 | >2 |
a
Strains were challenged with the MIC90 for S. pneumoniae strains (0.5 mg/ml). The limit of detection of this assay was 50 CFU/ml.