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. 2021 Nov 2;12:761167. doi: 10.3389/fphar.2021.761167

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Copyright © 2021 Shi, Zuo, Yu, Lao, Li, Xu and Lv.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Changes of laboratory test values before and after tigecycline treatment in DILI patients (n = 55). Horizontal bars represent the median value, boxes represent the interquartile range and whiskers indicate the minimum and maximum value. Wilcoxon’s test was used to compared baseline and after tigecycline treatment’s biochemical test values. *p < 0.0001. Abbreviation: TB, total bilirubin; ALT, alanine aminotransferase; AST, aspartate aminotransferase; ALP, alkaline phosphatase; ALB, albumin; PT, prothrombin time; DILI, drug-induced liver injury.