Table 3.
Parental ACE Measure | Epigenetic Target | r | p |
---|---|---|---|
Total ACEs | Parent COMT Parent DRD2 Parent GR Parent SERT |
−0.069 −0.091 −0.209 −0.151 |
0.728 0.644 0.287 0.443 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
0.045 −0.264 −0.088 −0.189 |
0.725 0.037 0.495 0.138 |
|
Total Maltreatment | Parent COMT Parent DRD2 Parent GR Parent SERT |
−0.170 −0.120 −0.217 −0.127 |
0.388 0.543 0.267 0.520 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
0.029 −0.272 −0.077 −0.113 |
0.823 0.031 0.548 0.378 |
|
Total Household Dysfunction | Parent COMT Parent DRD2 Parent GR Parent SERT |
0.051 −0.046 −0.165 −0.152 |
0.798 0.817 0.401 0.440 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
0.054 −0.202 −0.081 −0.232 |
0.677 0.113 0.528 0.067 |
Note: ACE = adverse childhood experience, COMT = catechol-O-methyltransferase, DRD2 = dopamine receptor, GR = glucocorticoid receptor, SERT = serotonin transporter, r = Pearson’s correlation, p = p value.