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. 2021 Apr 15;5(2):9. doi: 10.3390/epigenomes5020009

Table 4.

Results from the correlational analyses between parental ACE measures and epigenetic targets for male offspring.

Parental ACE Measure Epigenetic Target r p
Total ACEs Parent COMT
Parent DRD2
Parent GR
Parent SERT
−0.681
−0.521
−0.354
−0.240
0.030
0.122
0.316
0.504
Youth COMT
Youth DRD2
Youth GR
Youth SERT
0.052
0.125
0.059
−0.094
0.824
0.589
0.798
0.686
Total Maltreatment Parent COMT
Parent DRD2
Parent GR
Parent SERT
−0.463
−0.570
−0.555
−0.512
0.177
0.085
0.096
0.131
Youth COMT
Youth DRD2
Youth GR
Youth SERT
0.138
−0.100
−0.099
−0.111
0.552
0.666
0.668
0.633
Total Household Dysfunction Parent COMT
Parent DRD2
Parent GR
Parent SERT
−0.737
−0.308
−0.010
0.154
0.015
0.386
0.979
0.671
Youth COMT
Youth DRD2
Youth GR
Youth SERT
−0.063
0.133
0.000
−0.327
0.786
0.565
0.998
0.148

Note: ACE = adverse childhood experience, COMT = catechol-O-methyltransferase, DRD2 = dopamine receptor, GR = glucocorticoid receptor, SERT = serotonin transporter, r = Pearson’s correlation, p = p value.