Table 4.
Parental ACE Measure | Epigenetic Target | r | p |
---|---|---|---|
Total ACEs |
Parent COMT Parent DRD2 Parent GR Parent SERT |
−0.681 −0.521 −0.354 −0.240 |
0.030 0.122 0.316 0.504 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
0.052 0.125 0.059 −0.094 |
0.824 0.589 0.798 0.686 |
|
Total Maltreatment | Parent COMT Parent DRD2 Parent GR Parent SERT |
−0.463 −0.570 −0.555 −0.512 |
0.177 0.085 0.096 0.131 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
0.138 −0.100 −0.099 −0.111 |
0.552 0.666 0.668 0.633 |
|
Total Household Dysfunction |
Parent COMT Parent DRD2 Parent GR Parent SERT |
−0.737 −0.308 −0.010 0.154 |
0.015 0.386 0.979 0.671 |
Youth COMT Youth DRD2 Youth GR Youth SERT |
−0.063 0.133 0.000 −0.327 |
0.786 0.565 0.998 0.148 |
Note: ACE = adverse childhood experience, COMT = catechol-O-methyltransferase, DRD2 = dopamine receptor, GR = glucocorticoid receptor, SERT = serotonin transporter, r = Pearson’s correlation, p = p value.