AML |
Acute myeloid leukemia |
LSC |
Leukemic stem cell |
IDH |
Isocitrate dehydrogenase |
α-KG |
Alpha-keto-glutarate |
2-HG |
2-Hydroxyglutarate |
JHDM |
Jumonji-C domain histone demethylase |
mut-IDH |
Mutated Isocitrate dehydrogenase |
TET |
Ten-Eleven-Translocation |
PRC2 |
Polycomb repressive complex 2 |
EZH2 |
Enhancer of zeste 2 polycomb repressive complex 2 subunit |
DNMT |
DNA methyltransferase |
5AZA-CdR |
5-Aza-2′-deoxycytidine |
DZNep |
3-Deazaneplanocin-A |
H3K27me3 |
Histone 3-lysine 27-trimethylated |
H3K9me2 |
Histone 3-lysine 9-diimethylated |