Table 1.

Aberrantly methylated genes of various tumor types and reported gender difference.

Gene	Cancers	Reported Gender Difference
ANK1	Pancreatic cancer [166], lung cancer (LC) [142]
APC	Melanoma [167], Nasopharyngeal carcinoma [168], LC [65]
CDH1	Breast cancer (BC) [169], Cervical cancer [127], Head and neck cancer (HNC) [125], LC [65], Oral cancer [170], GC [162]	GC [162]
CDH11	Melanoma [171]
CDH13	BC [143], CRC [172], LC [65], Melanoma [167], Prostate Cancer [173]	LC [174]
CLDN11	Melanoma [171]
COL1A2	Melanoma [171]
DAPK	Cervical cancer [127], HNC [125], LC [130], Nasopharyngeal carcinoma [168], Prostate Cancer [173], Gastric cancer (GC) [162]	GC [162]
EGFR	BC [175], LC [176]
ERα	LC [81]	LC [81]
ESR1	LC [174]	LC [174]
FHIT	BC [141], Cervical cancer [177], Liver cancer [178], LC [141]
GATA5	LC [174]	LC [174]
GSTP1	GC [115]	GC [115]
HACE1	GC [160]	GC [160]
hMLH1	BC [169], LC [179], Colorectal cancer (CRC) [88] GC [115]	CRC [88], GC [115]
HOXA11	GC [161]	GC [161]
HOXA9	Melanoma [171]
KCNH8	LC [180]	LC [180]
L1TD1	LC [133]
LOX	Melanoma [171]
MAPK13	Melanoma [171]
MGMT	CRC [112], LC [37], GC [115]	LC [37], GC [115]
MGMT	LC [37], Glioblastoma [181]	LC [37], CRC [114]
p14(ARF)	CRC [89]	CRC [88]
p16INK4a	BC [169], Cervical cancer [127], HNC [125], LC [65], Melanoma [167], Prostate Cancer [173]	CRC [148], HCC [164,165]
PAX6	LC [174]	LC [174]
PTEN	Melanoma [171]
RARß	LC [65], Melanoma [167], Oral cancer [170], Prostate cancer [126]	LC [180]
RASSF1	BC [169], Endometrial cancer [182], LC [65], Melanoma [167], Nasopharyngeal carcinoma [168], Oral cancer [170], Prostate Cancer [173], CRC [112]	CRC [112], LC [111], BC [103]
RNF	LC [183]
SPAG6	LC [133]
SYK	Melanoma [171]
THBS1	GC [162]	GC [162]
TIMP3	GC [162]	GC [162]
TNFSF10D	Melanoma [171]
ZAR1	Bladder cancer [184], Cervical cancer [185], LC [144]
ZNF677	LC [134]