Table 3.
Characteristics of Cases with Varicella Zoster Anterior Uveitis with and without Aqueous Polymerase Chain Reaction Testing for Varicella Zoster Virus
| Characteristic | Without PCR* Testing | With PCR* Testing | P-value |
|---|---|---|---|
| Number cases | 98 | 25 | |
| Demographics | |||
| Age, median, years (25th 75th percentile) | 66 (56, 74) | 55 (50, 70) | 0.07 |
| Age category, years (%) | 0.13 | ||
| ≤16 | 2 | 0 | |
| 17–50 | 12 | 24 | |
| 51–60 | 25 | 32 | |
| >60 | 61 | 44 | |
| Gender (%) | 0.16 | ||
| Men | 37 | 52 | |
| Women | 63 | 48 | |
| Race/ethnicity (%) | 0.01 | ||
| White, non-Hispanic | 81 | 52 | |
| Black, non-Hispanic | 3 | 4 | |
| Hispanic | 3 | 0 | |
| Asian, Pacific Islander | 10 | 20 | |
| Other | 1 | 8 | |
| Missing/unknown | 2 | 16 | |
| Uveitis History | |||
| Uveitis course (%) | 0.62 | ||
| Acute, monophasic | 34 | 46 | |
| Acute, recurrent | 5 | 8 | |
| Chronic | 42 | 38 | |
| Indeterminate | 18 | 8 | |
| Laterality (%) | 0.91 | ||
| Unilateral | 96 | 96 | |
| Bilateral | 4 | 4 | |
| Ophthalmic examination | |||
| Cornea | 0.74 | ||
| No keratitis | 71 | 68 | |
| Keratitis | 29 | 32 | |
| Keratic precipitates (%) | 0.63 | ||
| None | 31 | 28 | |
| Fine | 44 | 36 | |
| Round | 9 | 16 | |
| Stellate | 4 | 0 | |
| Mutton Fat | 11 | 20 | |
| Other | 1 | 0 | |
| Anterior chamber cells (%) | 0.33 | ||
| Grade ½+ | 32 | 8 | |
| 1+ | 37 | 16 | |
| 2+ | 23 | 48 | |
| 3+ | 4 | 20 | |
| Anterior chamber flare (%) | 0.76 | ||
| Grade 0 | 54 | 60 | |
| 1+ | 36 | 28 | |
| 2+ | 10 | 12 | |
| Iris (%) | |||
| Normal | 83 | 64 | 0.06 |
| Posterior synechiae | 6 | 8 | 0.66 |
| Sectoral iris atrophy | 9 | 16 | 0.25 |
| Other iris abnormality | 6 | 24 | 0.001 |
| Intraocular pressure (IOP), involved eyes | |||
| Median, mm Hg (25th, 75th percentile) | 15 (12, 20) | 16 (14, 30) | 0.12 |
| Percent patients with IOP>24 mm Hg either eye | 21 | 36 | 0.29 |
| Vitreous cells (%) | 0.08 | ||
| Grade 0 | 89 | 84 | |
| ½+ | 10 | 8 | |
| ≥1+ | 1 | 8 | |
| Immune compromised host (%) | 8 | 5 | 0.22 |
| Dermatomal Herpes zoster (%) | 98 | 40 | <0.0001 |
*
PCR = polymerase chain reaction; testing for varicella zoster virus in aqueous.