Table 4.
Characteristics of Cases with Syphilitic Uveitis by Anatomic Class
| Characteristic/Uveitic Anatomic Class | Anterior Uveitis | Intermediate Uveitis | Posterior Uveitis | Panuveitis |
|---|---|---|---|---|
| Number cases | 32 | 85 | 35 | 70 |
| Demographics | ||||
| Age, median, years (25th 75th percentile) | 50 (34, 61) | 48 (38, 55) | 52 (39, 55) | 46 (35, 56) |
| Gender (%) | ||||
| Men | 84 | 79 | 83 | 82 |
| Women | 16 | 21 | 17 | 18 |
| Race/ethnicity (%) | ||||
| White, non-Hispanic | 50 | 45 | 57 | 57 |
| Black, non-Hispanic | 28 | 12 | 3 | 15 |
| Hispanic | 6 | 18 | 6 | 7 |
| Asian, Pacific Islander | 9 | 5 | 3 | 3 |
| Other | 6 | 5 | 19 | 7 |
| Missing | 1 | 15 | 12 | 11 |
| Uveitis History | ||||
| Uveitis course (%) | ||||
| Acute, monophasic | 31 | 62 | 62 | 69 |
| Acute, recurrent | 0 | 4 | 3 | 0 |
| Chronic | 41 | 21 | 26 | 23 |
| Indeterminate | 28 | 12 | 9 | 8 |
| Laterality (%) | ||||
| Unilateral | 56 | 35 | 46 | 53 |
| Bilateral | 44 | 65 | 54 | 47 |
| Ophthalmic examination | ||||
| Keratic precipitates (%) | ||||
| None | 41 | 40 | 94 | 23 |
| Fine | 28 | 36 | 6 | 49 |
| Round | 13 | 12 | 0 | 17 |
| Stellate | 0 | 4 | 0 | 3 |
| Mutton Fat | 19 | 8 | 0 | 9 |
| Anterior chamber cells (%) | ||||
| Grade 0 | 0 | 26 | 94 | 3 |
| ½+ | 6 | 9 | 3 | 14 |
| 1+ | 38 | 24 | 0 | 20 |
| 2+ | 44 | 14 | 3 | 40 |
| 3+ | 13 | 22 | 0 | 20 |
| 4+ | 0 | 5 | 0 | 3 |
| Anterior chamber flare (%) | ||||
| Grade 0 | 53 | 47 | 97 | 31 |
| 1+ | 25 | 27 | 3 | 33 |
| 2+ | 19 | 13 | 0 | 24 |
| 3+ | 3 | 11 | 0 | 10 |
| 4+ | 0 | 2 | 0 | 1 |
| Iris (%) | ||||
| Normal | 90 | 90 | 100 | 86 |
| Posterior synechiae | 6 | 8 | 0 | 14 |
| Iris nodules | 9 | 2 | 0 | 0 |
| Intraocular pressure (IOP), involved eyes | ||||
| Median, mm Hg (25th, 75th percentile) | 15 (14, 17) | 15 (13, 18) | 15 (12, 20) | 15 (12, 17) |
| Percent patients with IOP>24 mm Hg either eye | 6 | 9 | 28 | 4 |
| Vitreous cells (%) | ||||
| Grade 0 | 59 | 1 | 43 | 7 |
| ½+ | 25 | 8 | 6 | 10 |
| 1+ | 13 | 26 | 17 | 36 |
| 2+ | 3 | 35 | 20 | 23 |
| 3+ | 0 | 21 | 11 | 20 |
| 4+ | 0 | 8 | 3 | 4 |
| Vitreous haze (%) | ||||
| Grade 0 | 0 | 18 | 51 | 23 |
| ½+ | 0 | 13 | 11 | 10 |
| 1+ | 0 | 27 | 9 | 23 |
| 2+ | 0 | 15 | 17 | 26 |
| 3+ | 0 | 12 | 6 | 17 |
| 4+ | 0 | 15 | 6 | 1 |
| Vitreous snowballs (%) | 0 | 9 | 14 | 0 |
| Optic disc edema (%) | 1 | 21 | 14 | 26 |
| Placoid inflammation of the retinal pigment epithelium (%) | 0 | 0 | 34 | 36 |
| Multifocal inflammation of the retina/retinal pigment epithelium (%) | 0 | 0 | 49 | 43 |
| Necrotizing retinitis (%) | 0 | 0 | 12 | 16 |
| Occlusive retinal vasculitis (%) | 0 | 2 | 0 | 9 |
| Retinal vascular sheathing or leakage (%) | 0 | 34 | 48 | 41 |
| Systemic disease | ||||
| HIV-infected* (%) | 47 | 35 | 40 | 36 |
*
HIV = human immunodeficiency virus.