Table 1.
Characteristics of Patients with Sarcoid Uveitis
| Characteristic | Result |
|---|---|
| Number cases | 278 |
| Demographics | |
| Age, median, years (25th 75th percentile) | 49 (39, 61) |
| Gender (%) | |
| Men | 29 |
| Women | 71 |
| Race/ethnicity (%) | |
| White, non-Hispanic | 37 |
| Black, non-Hispanic | 26 |
| Hispanic | 1 |
| Asian, Pacific Islander | 24 |
| Other | 9 |
| Missing | 3 |
| Uveitis History | |
| Uveitis course (%) | |
| Acute, monophasic | 5 |
| Acute, recurrent | 7 |
| Chronic | 80 |
| Indeterminate | 8 |
| Laterality (%) | |
| Unilateral | 18 |
| Unilateral, alternating | 1 |
| Bilateral | 82 |
| Ophthalmic examination | |
| Keratic precipitates (%) | |
| None | 52 |
| Fine | 18 |
| Round | 6 |
| Stellate | 0 |
| Mutton Fat | 23 |
| Anterior chamber cells (%) | |
| Grade 0 | 15 |
| ½+ | 24 |
| 1+ | 28 |
| 2+ | 25 |
| 3+ | 7 |
| 4+ | 1 |
| Hypopyon (%) | 1 |
| Anterior chamber flare (%) | |
| Grade 0 | 60 |
| 1+ | 30 |
| 2+ | 9 |
| 3+ | 1 |
| 4+ | 0 |
| Iris (%) | |
| Normal | 64 |
| Posterior synechiae | 27 |
| Iris nodules | 12 |
| Sectoral iris atrophy | 0 |
| Patchy iris atrophy | 1 |
| Diffuse iris atrophy | 0 |
| Heterochromia | 0 |
| Intraocular pressure (IOP), involved eyes | |
| Median, mm Hg (25th, 75th percentile) | 16 (13, 19) |
| Proportion patients with IOP>24 mm Hg either eye (%) | 10 |
| Vitreous cells (%) | |
| Grade 0 | 31 |
| ½+ | 21 |
| 1+ | 31 |
| 2+ | 14 |
| 3+ | 3 |
| 4+ | 0 |
| Vitreous haze (%) | |
| Grade 0 | 61 |
| ½+ | 11 |
| 1+ | 20 |
| 2+ | 5 |
| 3+ | 2 |
| 4+ | 0 |
| Vitreous snowballs (%) | 17 |
| Pars plana snowbanks (%) | 1 |
| Choroidal nodule (%) | 2 |
| Multifocal choroiditis (%) | 30 |
| Retinal vascular sheathing (%) | 18 |
| Anatomic class (%) | |
| Anterior uveitis | 40 |
| Intermediate uveitis | 19 |
| Posterior uveitis | 4 |
| Panuveitis | 37 |
| Evidence of sarcoidosis (%) | |
| Non-caseating granuloma on tissue biopsy* | 58 |
| Bilateral hilar adenopathy of chest imaging† | 79 |
| Non-specific tests for sarcoidosis (%) | |
| Angiotensin converting enzyme (ACE) | 52 |
| Lysozyme | 12 |
*
161 of 161 patients biopsied had a “positive” biopsy demonstrating non-caseating granulomata.
†
174 of 242 patients (72%) had a chest radiograph with bilateral hilar adenopathy, and 134 of 164 patients (82%) undergoing computerized tomography had bilateral hilar adenopathy.