Table 2.
Characteristics of Sarcoid Uveitis by Anatomic Class of the Uveitis
| Characteristic/Anatomic Class | Anterior uveitis | Intermediate uveitis | Posterior Uveitis | Panuveitis |
|---|---|---|---|---|
| Number cases | 112 | 52 | 12 | 102 |
| Demographics | ||||
| Age, median, years (25th 75th percentile) | 46 (37, 55) | 52 (43, 67) | 53 (50, 64) | 51 (35, 63) |
| Gender (%) | ||||
| Men | 24 | 29 | 33 | 33 |
| Women | 76 | 71 | 67 | 67 |
| Race/ethnicity (%) | ||||
| White, non-Hispanic | 30 | 63 | 42 | 31 |
| Black, non-Hispanic | 49 | 6 | 0 | 15 |
| Hispanic | 0 | 2 | 0 | 2 |
| Asian, Pacific Islander | 7 | 13 | 33 | 45 |
| Other | 7 | 12 | 25 | 4 |
| Missing | 7 | 4 | 0 | 3 |
| Uveitis History | ||||
| Uveitis course (%) | ||||
| Acute, monophasic | 10 | 0 | 0 | 3 |
| Acute, recurrent | 14 | 2 | 0 | 3 |
| Chronic | 63 | 96 | 92 | 78 |
| Indeterminate | 13 | 2 | 8 | 16 |
| Laterality (%) | ||||
| Unilateral | 24 | 19 | 42 | 7 |
| Unilateral, alternating | 2 | 0 | 0 | 0 |
| Bilateral | 74 | 81 | 58 | 93 |
| Ophthalmic examination | ||||
| Keratic precipitates (%) | ||||
| None | 46 | 75 | 92 | 43 |
| Fine | 19 | 15 | 8 | 20 |
| Round | 8 | 0 | 0 | 8 |
| Stellate | 1 | 0 | 0 | 0 |
| Mutton Fat | 27 | 10 | 0 | 29 |
| Anterior chamber cells (%) | ||||
| Grade 0 | 4 | 35 | 75 | 12 |
| ½+ | 25 | 27 | 17 | 24 |
| 1+ | 32 | 13 | 8 | 32 |
| 2+ | 30 | 19 | 0 | 24 |
| 3+ | 7 | 6 | 0 | 8 |
| 4+ | 2 | 0 | 0 | 1 |
| Hypopyon (%) | 1 | 0 | 0 | 0 |
| Anterior chamber flare (%) | ||||
| Grade 0 | 63 | 81 | 100 | 42 |
| 1+ | 29 | 15 | 0 | 39 |
| 2+ | 6 | 2 | 0 | 18 |
| 3+ | 2 | 0 | 0 | 1 |
| 4+ | 0 | 2 | 0 | 0 |
| Iris (%) | ||||
| Normal | 61 | 60 | 100 | 66 |
| Posterior synechiae | 33 | 29 | 0 | 23 |
| Iris nodules | 13 | 10 | 0 | 16 |
| Sectoral iris atrophy | 0 | 0 | 0 | 0 |
| Patchy iris atrophy | 1 | 2 | 0 | 2 |
| Intraocular pressure (IOP), involved eyes | ||||
| Median, mm Hg (25th, 75th percentile) | 16 (13, 19) | 16 (14, 18) | 15 (14, 17) | 16 (13, 18) |
| Percent patients with IOP>24 mm Hg either eye | 8 | 8 | 0 | 16 |
| Vitreous cells (%) | ||||
| Grade 0 | 55 | 10 | 25 | 17 |
| ½+ | 27 | 21 | 17 | 14 |
| 1+ | 14 | 52 | 33 | 39 |
| 2+ | 3 | 15 | 25 | 24 |
| 3+ | 1 | 2 | 0 | 6 |
| Vitreous haze (%) | ||||
| Grade 0 | 86 | 46 | 42 | 44 |
| ½+ | 6 | 17 | 17 | 14 |
| 1+ | 5 | 29 | 33 | 28 |
| 2+ | 1 | 4 | 8 | 11 |
| 3+ | 1 | 4 | 0 | 3 |
| Vitreous snowballs (%) | 0 | 58 | 8 | 26 |
| Pars plana snowbanks (%) | 0 | 4 | 0 | 0 |
| Choroidal nodule (%) | 0 | 0 | 17 | 5 |
| Multifocal choroiditis (%) | 0 | 0 | 92 | 73 |
| Retinal vascular sheathing (%) | 0 | 27 | 49 | 28 |
| Evidence of sarcoidosis (%) | ||||
| Non-caseating granuloma on tissue biopsy | 60 | 54 | 58 | 59 |
| Bilateral hilar adenopathy of chest imaging | 82 | 85 | 75 | 74 |
| Non-specific tests for sarcoidosis (%) | ||||
| Angiotensin converting enzyme (ACE) | 45 | 51 | 58 | 59 |
| Lysozyme | 14 | 0 | 0 | 17 |