Distributions of biomechanical parameter values for sclerotic cGVHD patients and post-HCT controls. Patients with sclerotic cGVHD (red boxes) had increased stiffness and frequency and decreased relaxation time and creep compared with post-HCT controls (blue boxes). Patients with sclerotic cGVHD and post-HCT controls were compared by Wilcoxon rank-sum test using averages across the 18 sites (solid boxes, n for patients with cGVHD = 13, n for post-HCT control = 11) and averages across the 12 supine sites (diagonal pattern, n for patients with cGVHD = 15, n for post-HCT control = 11); ∗P < 0.05. Frequency and stiffness (top row) values are expected to be higher for sclerotic skin than for healthy skin, whereas relaxation time and creep (bottom row) values are expected to be lower for sclerotic skin. Logarithmic decrement (overall: P = 0.209, supine: P = 0.209) is not shown. cGVHD, chronic graft-versus-host disease; HCT, hematopoietic cell transplantation; Q, quartile.