Table 2.
Inactivated/ Live attenuated virus Vaccines and stages of development
| Developer / Researcher | Stage of Development | Product Description |
|---|---|---|
| Beijing Institute of Biological Products/ Sinopharm | Phase III | Inactivated, (BBIBP-CorV)51 |
| Bharat Biotech/ Indian Council of Medical Research/ National Institute of Virology/ Ocugen/ Precisa Medicamentos | Phase III | Inactivated; whole virion (COVAXIN) (BBV152)52; 53; 54 |
| Institute of Medical Biology, Chinese Academy of Medical Sciences | Phase III | Inactivated55 |
| Research Institute for Biological Safety Problems, Republic of Kazakhstan | Phase III | Inactivated, (QazCovid-in®) |
| Sinovac/ Instituto Butantan/ Bio Farma | Phase III | Inactivated (inactivated + alum); CoronaVac (formerly PiCoVacc)52,56; 57 |
| Wuhan Institute of Biological Products/ Sinopharm | Phase III | Inactivated 58 |
| Erciyes University | Phase II | Inactivated; (ERUCOV-VAC) |
| Shenzhen Kangtai Biological Products Co.,Ltd./ Beijing Minhai Biotechnology Co., Ltd. | Phase II | Inactivated SARS-CoV-2 vaccine (Vero cell) |
| Valneva/ Dynavax/ National Institute for Health Research, United Kingdom | Phase I/II | Inactivated (Inactivated + CpG 1018), VLA2001 |
| Shifa Pharmed Industrial Co | Phase I | COVID-19 inactivated vaccine (COVIran Barekat) |
| Government Pharmaceutical Organization (GPO; Thailand) / Dynavax / PATH | Pre-clinical | Egg-based, inactivated, whole chimeric Newcastle Disease Virus (NDV) expressing membrane-anchored pre-fusion-stabilized trimeric SARS-CoV-2 S protein (Hexapro) + CpG 1018 |
| Institute Butantan (Brazil) / Dynavax / PATH | Pre-clinical | |
| Institute of Vaccines and Medical Biologicals (IVAC; Vietnam) / Dynavax / PATH | Pre-clinical | |
| KM Biologics | Pre-clinical | Inactivated (inactivated + alum) |
| Kocak Farma Ilac ve Kimya San. A.S. | Pre-clinical | Inactivated |
| National Research Centre, Egypt | Pre-clinical | Inactivated whole virus |
| Osaka University / BIKEN / NIBIOHN | Pre-clinical | Inactivated |
| Selcuk University | Pre-clinical | Inactivated |
| Sinovac/ Dynavax | Pre-clinical | Inactivated + adjuvant (CpG 1018) |
| Live attenuated virus Vaccines and stages of development | ||
| Codagenix / Serum Institute of India | Phase I | Single-dose, intranasal, live attenuated vaccine, (COVI-VAC) |
| Indian Immunologicals Ltd/ Griffith University | Pre-clinical | Codon deoptimized live attenuated virus |
| Mehmet Ali Aydinlar University/ Acıbadem Labmed Health Services A.S. | Pre-clinical | Codon deoptimized live attenuated vaccines |
| Meissa Vaccines | Pre-clinical | MV-014-210 |