Table 1.

Evaluation of Reaction Conditions for the Direct Arylation of 1-Fluoronaphthalene (1a)

entry	deviation on reaction conditions	yield (%)a
1	none	81
2	Cy3P, instead of tBuPCy2	50
3	Cy2PPh, instead of tBuPCy2	41
4	tBu3P, instead of tBuPCy2	35
5	Ph3P, instead of tBuPCy2	10
6	(o-Tolyl)3P, instead of tBuPCy2	<5
7	AgOAc (1 equiv), instead of Ag2O	38
8	Ag2CO3, instead of Ag2O	43
9	AgNO3, instead of Ag2O	56
10	K2CO3, instead of Cs2CO3	24
11	Na2CO3, instead of Cs2CO3	20
12	without Pd(OAc)2	<5
13	without tBuPCy2	<5
14	without Ag2O	<5

^aDetermined by ¹⁹F NMR in CDCl₃ with C₆H₅F as internal standard.