Appendix 10—figure 1. Input used for simulations of exponential and asymptotically linear growth.

For both simulations, a linear fit of the division length versus birth length is used to define a target length (A). The length added during the V-snap at division is randomly drawn from the distribution corresponding to the division length of the simulated cell (B). The experimental data is divided into three subpopulations according to division length (red, green, and orange distributions), as the average length added during V-snap decreases with division length (dashed lines). The asymmetry of the daughter cells is randomly drawn from the distribution corresponding to the combined length of the simulated daughters (C). As the asymmetry is lower for the smallest daughter cells, the experimental data is divided into two subpopulations (red and green distributions). For the simulation of exponential growth, two noise sources are needed as input. The time-additive noise is randomly drawn from the distribution of deviations from target growth times (D). This distribution is obtained from the deviations of single-cell growth times from the average of their birth length bin. All growth variability not captured by growth time variations is calculated for four narrow birth length bins (blue, orange, green, and red points) (E). From the distribution of deviations of added lengths from a linear fit for each initial size bin, a size-additive noise term is randomly drawn. For the linear growth simulation, only a single additive noise term is required, which is randomly drawn from the distribution of deviations of cells lengths at division from the target division length (F).