Gao 2013.
Study characteristics | ||
Methods |
Randomised, cross‐over, self‐control study with 2 arms
Recruitment period: n.r.
Masking: n.r. Baseline patient characteristics: n.r. Follow‐up: n.r. |
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Participants |
Inclusion criteria: n.r. Exclusion criteria: n.r. Mean/median age (range), years: n.r. Gender: n.r. Tumour/cancer type: n.r. Chemotherapy regimen: cisplatin‐based chemotherapy Country: n.r. |
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Interventions |
Cross‐over study Experimental: arm A: palonosetron Day 1: palonosetron 0. 25 mg i.v. + dexamethasone 10 mg i.v. Day 2: dexamethasone 10 mg i.v. Day 3: palonosetron 0. 25 mg i.v. + dexamethasone 10 mg i.v. Experimental: arm B: granisetron Days 1 to 3: granisetron 3 mg i.v. + dexamethasone 10 mg i.v. |
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Outcomes | not reported | |
Notes |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: randomised trial but method of randomisation not described |
Allocation concealment (selection bias) | Unclear risk | Comment: allocation concealment not reported |
Blinding of participants and personnel (performance bias) Blinding of participants | Unclear risk | Comment: blinding not reported |
Blinding of participants and personnel (performance bias) Blinding of personnel | Unclear risk | Comment: blinding not reported |
Blinding of outcome assessment (detection bias) Subjective outcomes (Patient reported outcomes) | Unclear risk | Comment: blinding not reported |
Incomplete outcome data (attrition bias) Subjective outcomes (Patient reported outcomes) | Unclear risk | Comment: no outcomes reported |
Selective reporting (reporting bias) | Unclear risk | Comment: conference abstract, not evaluable |
Other bias | Unclear risk | Comment: conference abstract, not evaluable |