Stewart 1996.
Study characteristics | ||
Methods |
Randomised trial with 2 arms
Recruitment period: n.r. Enrolled/randomised patient number: n.r. Masking: double‐blind Baseline patient characteristics: n.r. Follow‐up: n.r. |
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Participants |
Inclusion criteria: n.r. Exclusion criteria: n.r. Mean/median age (range), years: n.r. Gender: n.r. Tumour/cancer type: n.r. Chemotherapy regimen: cisplatin Country: n.r. |
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Interventions |
Experimental: arm A: granisetron granisetron + dexamethasone (8 mg i.v., then treatment 4 mg t.d.s. for 3 days afterwards) Experimental: arm B: ondansetron ondansetron + dexamethasone (8 mg i.v., then treatment 4 mg t.d.s. for 3 days afterwards) |
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Outcomes |
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Notes |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: randomised study but method of randomisation not described |
Allocation concealment (selection bias) | Unclear risk | Comment: allocation concealment not reported |
Blinding of participants and personnel (performance bias) Blinding of participants | Low risk | Comment: double‐blind |
Blinding of participants and personnel (performance bias) Blinding of personnel | Low risk | Comment: double‐blind |
Blinding of outcome assessment (detection bias) Subjective outcomes (Patient reported outcomes) | Low risk | Comment: both patients and personnel were blinded towards the intervention and thus had no influence on outcome assessment |
Incomplete outcome data (attrition bias) Subjective outcomes (Patient reported outcomes) | Unclear risk | Comment: not reported |
Selective reporting (reporting bias) | Unclear risk | Comment: not evaluable, conference abstract only |
Other bias | Unclear risk | Conference abstract, not evaluable |