Table 3.
Effects of bisdemethoxycurcumin on the mitochondrial redox system of jejunum and ileum in LPS-treated broilers.
| Items | LPS (-) | LPS (+) | SEM | P | ||||
|---|---|---|---|---|---|---|---|---|
| CON | BIS | LPS | L-BIS | Diet | Stress | D × S | ||
| Jejunal mitochondria | ||||||||
| MDA (nmol/mg protein) | 2.61c | 3.14bc | 5.75a | 4.33ab | 0.216 | 0.313 | <0.001 | 0.032 |
| GSH (mg/g protein) | 11.45a | 12.42a | 7.50b | 6.69b | 0.219 | 0.859 | <0.001 | 0.053 |
| MnSOD (U/mg protein) | 20.56 | 23.07 | 14.87 | 17.56 | 0.227 | <0.001 | <0.001 | 0.845 |
| Ileal mitochondria | ||||||||
| MDA (nmol/mg protein) | 2.20c | 2.19c | 6.28a | 4.87b | 0.165 | 0.042 | <0.001 | 0.044 |
| GSH (mg/g protein) | 11.67a | 11.10a | 7.15b | 8.85b | 0.257 | 0.283 | <0.001 | 0.036 |
| MnSOD (U/mg protein) | 21.01a | 21.49a | 16.00b | 18.79c | 0.179 | <0.001 | <0.001 | 0.003 |
MDA: malondialdehyde; GSH: glutathione; MnSOD: superoxide dismutase. CON: broiler chickens fed a basal diet; BIS: broiler chickens fed a basal diet with 150 mg/kg bisdemethoxycurcumin; LPS: broiler chickens fed a basal diet with LPS injection; L-BIS: broiler chickens fed a basal diet with LPS injection and 150 mg/kg bisdemethoxycurcumin. Diet: 0 or 150 mg/kg bisdemethoxycurcumin treatment; Stress: saline or LPS challenge; D × S: interaction between bisdemethoxycurcumin treatment and LPS challenge. Data were expressed as means and SEM, n = 8 replicates per treatment and 10 birds per replication. Means within a row with no common superscript differ P < 0.05.