Table 2.
The comparison of plaque characteristics and lesion-specified fat attenuation index (FAIlesion) in different lesions.
Total | FFR <0.8 | FFR ≥ 0.8 | P-value | |
---|---|---|---|---|
Vessels (n) | 246 | 91 | 155 | |
ICA stenosis, % | 62 ± 3 | 72 ± 9 | 56 ± 12 | <0.01 |
<50% (n) | 41 | 0 | 41 | <0.01 |
50–70% (n) | 132 | 39 | 93 | |
>70% (n) | 73 | 52 | 21 | |
CTA stenosis, % | 52 ± 22 | 66 ± 13 | 44 ± 22 | <0.01 |
TPV (mm 3 ) | 134 | 157 | 126 | <0.01 |
(87, 208) | (102, 248) | (77, 188) | ||
HD-P volume (mm3) | 60 (20, 113) | 82 (31, 132) | 48 (16, 100) | 0.02 |
HD-P ratio, % | 50 (17, 73) | 50 (20, 74) | 51 (12, 73) | 0.82 |
ID-P volume (mm3) | 52 (27, 99) | 58 (33, 110) | 50 (24, 87) | 0.08 |
ID-P ratio, % | 39 (23, 58) | 37 (22, 54) | 37 (25, 62) | 0.31 |
LD-P volume (mm3) | 9 (1, 19) | 11 (1, 21) | 7 (1, 16) | 0.05 |
LD-P ratio, % | 6 (1, 12) | 6 (1, 12) | 5 (1, 12) | 0.47 |
Non-calcified plaque | 64.4 | 69.4 | 59.4 | 0.04 |
volume (mm3) | (31.2, 118.9) | (39.0, 139.9) | (27.7, 115.1) | |
High-risk plaque features | ||||
Low-attenuation plaque | 28 (11.4%) | 13 (14.3%) | 15 (9.7%) | 0.27 |
Napkin-ring sign | 20 (8.1%) | 7 (7.7%) | 13 (8.4%) | 0.85 |
Spotty calcification | 61 (25.2%) | 19 (20.9%) | 42 (27.1%) | 0.26 |
Positive remodeling | 139 (56.6%) | 46 (50.5%) | 93 (60.0%) | 0.15 |
Lesion with high-risk plaque | 53 (21.5%) | 24 (26.4%) | 29 (18.7%) | 0.16 |
FAIlesion (HU) | −74 ± 9 | −71 ± 8 | −76 ± 9 | <0.01 |
FAIlesion, lesion-specified fat attenuation index; ICA, invasive coronary angiography; CTA, computed tomography angiography; TPV, total plaque volume; HD-P, high-attenuation plaque component; ID-P, intermediate-attenuation plaque component; LD-P, low-attenuation plaque component; HU, Hounsfield unit.