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. 2021 Nov 3;8:755295. doi: 10.3389/fcvm.2021.755295

Table 2.

The comparison of plaque characteristics and lesion-specified fat attenuation index (FAIlesion) in different lesions.

Total FFR <0.8 FFR ≥ 0.8 P-value
Vessels (n) 246 91 155
ICA stenosis, % 62 ± 3 72 ± 9 56 ± 12 <0.01
<50% (n) 41 0 41 <0.01
50–70% (n) 132 39 93
>70% (n) 73 52 21
CTA stenosis, % 52 ± 22 66 ± 13 44 ± 22 <0.01
TPV (mm 3 ) 134 157 126 <0.01
(87, 208) (102, 248) (77, 188)
HD-P volume (mm3) 60 (20, 113) 82 (31, 132) 48 (16, 100) 0.02
HD-P ratio, % 50 (17, 73) 50 (20, 74) 51 (12, 73) 0.82
ID-P volume (mm3) 52 (27, 99) 58 (33, 110) 50 (24, 87) 0.08
ID-P ratio, % 39 (23, 58) 37 (22, 54) 37 (25, 62) 0.31
LD-P volume (mm3) 9 (1, 19) 11 (1, 21) 7 (1, 16) 0.05
LD-P ratio, % 6 (1, 12) 6 (1, 12) 5 (1, 12) 0.47
Non-calcified plaque 64.4 69.4 59.4 0.04
volume (mm3) (31.2, 118.9) (39.0, 139.9) (27.7, 115.1)
High-risk plaque features
Low-attenuation plaque 28 (11.4%) 13 (14.3%) 15 (9.7%) 0.27
Napkin-ring sign 20 (8.1%) 7 (7.7%) 13 (8.4%) 0.85
Spotty calcification 61 (25.2%) 19 (20.9%) 42 (27.1%) 0.26
Positive remodeling 139 (56.6%) 46 (50.5%) 93 (60.0%) 0.15
Lesion with high-risk plaque 53 (21.5%) 24 (26.4%) 29 (18.7%) 0.16
FAIlesion (HU) −74 ± 9 −71 ± 8 −76 ± 9 <0.01

FAIlesion, lesion-specified fat attenuation index; ICA, invasive coronary angiography; CTA, computed tomography angiography; TPV, total plaque volume; HD-P, high-attenuation plaque component; ID-P, intermediate-attenuation plaque component; LD-P, low-attenuation plaque component; HU, Hounsfield unit.