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. 2021 Nov 3;11:707402. doi: 10.3389/fcimb.2021.707402

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Copyright © 2021 Du, Ding, Na, Sun, Sun, Wang, He, Wang, Lu, Li, Guo, Zhang, Tian, Wang, Zhai, Yang and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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LEfSe analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) assignments of the mountain rural (MR), mountain urban (MU), plain rural (PR), and plain urban (PU) groups. (A) LEfSe analysis identified the predominant taxons of each group. Green represents the bacteria specific for the MR group, yellow represents the bacteria specific for the MU group, blue represents the bacteria specific for the PR group, and red represents the bacteria specific for the PU group. (B) Presentation of the altered KEGG pathways in each group. Grouping was performed in the same way as in Figure (A) LDA scores were calculated by LDA effect size, using the linear discriminant analysis to assess effect size of each differentially abundant bacterial taxa (A) or KEGG pathways (B).