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Pathway enrichment analyses of mutant genes in GIST. (A) Pathway enrichment of mutant genes in ten canonical oncogenic signaling pathways. (B,C) Enrichment analyses of gene function were performed based on 36 genes using the KEGG (B) or GO (C) pathway database. (D)Protein-protein interaction (PPI) networks were constructed based on 34 genes with mutations in GIST as well as KIT and PDGFRA using STRING software.
