TABLE 2.

KIT mutations in 49 GISTs.

Exon	Mutation site	Amino acid change	Mutation types	Mutation ratio% (n/n)
9	c.1502_1503insTGCCTT	p.S501delinsSAF	nonframeshift insertion	2.04% (1)
9	c.1502_1503insTGCCTA	p.S501delinsSAY	nonframeshift insertion	16.32% (8)
10	c.T1679A	p.A560N	missense	2.04% (1)
10	c.A1621C	p.M541L	missense	10.20% (5)
11	c.1648_1672del	p.K550fs	frameshift deletion	2.04% (1)
11	c.1652_1669del	p.551_557del	nonframeshift deletion	2.04% (1)
11	c.1653_1664del	p.551_555del	nonframeshift deletion	2.04% (1)
11	c.1658_1711del	p.553_571del	nonframeshift deletion	2.04% (1)
11	c.1659_1670del	p.553fs	frameshift deletion	2.04% (1)
11	c.1659_1712del	p.553_572del	nonframeshift deletion	2.04% (1)
11	c.1660_1683del	p.554_561del	nonframeshift deletion	2.04% (1)
11	c.1662_1688del	p.554_563del	nonframeshift deletion	2.04% (1)
11	c.1665_1718del	p.555_573del	nonframeshift deletion	2.04% (1)
11	c.1667_1672del	p.556_558del	nonframeshift deletion	4.08% (2)
11	c.1667_1681del	p.556_561del	nonframeshift deletion	4.08% (2)
11	c.1668_1679del	p.556_560del	nonframeshift deletion	2.04% (1)
11	c.1668_1670del	p.W557fs	frameshift deletion	2.04% (1)
11	c.T1669A	p.W557R	missense	6.12% (3)
11	c.T1669C	p.W557R	missense	2.04% (1)
11	c.1671_1685del	p.557_562del	nonframeshift deletion	2.04% (1)
11	c.A1672G	p.K558E	missense	2.04% (1)
11	c.1673_1714del	p.558_572del	nonframeshift deletion	2.04% (1)
11	c.1675_1677del	p.559_559del	nonframeshift deletion	2.04% (1)
11	c.1675_1695del	p.559_565del	nonframeshift deletion	2.04% (1)
11	c.1676_1726del	p.559_576del	nonframeshift deletion	2.04% (1)
11	c.T1676G	p.V559G	missense	4.08% (2)
11	c.T1676C	p.V559A	missense	6.12% (3)
11	c.T1676A	p.V559D	missense	6.12% (3)
11	c.T1679A	p.V560D	missense	2.04% (1)
11	c.T1679C	p.V560E	missense	2.04% (1)
11	c.T1680G	p.V560E	missense	2.04% (1)
11	c.1704_1727del	p.568_576del	nonframeshift deletion	4.08% (2)
11	c.1708_1709insACATAGACCCAACACAACTTCCTTATGATC	p.Y570delinsYIDPTQLPYDH	nonframeshift insertion	2.04% (1)
11	c.1728_1730del	p.576_577del	nonframeshift deletion	2.04% (1)
13	c.A1924G	p.K642E	missense	2.04% (1)
17	c.G2446C	p.D816H	missense	2.04% (1)