Fig. 1.

The details of the mutation identified in RdRp among Indian SARS-CoV-2 isolates. A) Schematic diagram of the domain architecture of RdRp. Each domain of RdRp is represented by a unique color. The interdomain borders are labeled with residue numbers.The mutations present in RdRp among the Indian isolates of SARS-CoV-2 are demonstrated in the schematics. B) The monthly data of ‘new sequences’ of SARS-CoV-2 and ‘appearance of new mutations’ were obtained from CoVal webserver. These data provided the time course of the SARS-CoV-2 samples reported from India. Based on the mutational analysis of RdRp by CoVal webserver, we observe that during initial phase COVID19 pandemic, the rate occurrence of new mutations were high but it slowed down as the time progresses. The X-axis shows months/year and Y-axis present on the left side of the graph represents number of SARS-CoV-2 samples reported per month while Y –axis on the right side shows the appearance of new mutation in RdRp per month. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)