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. 2021 Nov 16;11:22341. doi: 10.1038/s41598-021-01696-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The dose–response relationship of A10/8A7 and A10/16E8 to ADAMTS13 in ELISA tests. Each plot in the dose–response curves was obtained in triplicate. Chimeric A10 and 8A7 were used as positive and negative controls, respectively. The horizontal axis is the concentration of antibodies used in the ELISA test. The vertical axis is standardized absorbance values (arbitrary unit) relative to the values of chimeric A10.