Table 1.

Kinetic parameters of mA10, chimeric A10, A10/8A7, and A10/16E8 obtained by SPR analysis.

Antibody	kaa (1/Ms)	kdb (1/s)	KDc (nM)
mA10	6.04 × 104	3.62 × 10–4	5.99
Chimeric A10	7.27 × 103	2.03 × 10–5	2.80
A10/8A7	9.27 × 103	1.93 × 10–4	20.8
A10/16E8	1.24 × 104	6.30 × 10–5	5.07

^aAbbreviation: k_a, association rate constant.

^bAbbreviation: k_d, dissociation rate constant.

^cAbbreviation: K_D, dissociation constant.