Table 3.
Mean RMSD and Q-score for structural superposition between mA10 and each of two humanized A10 antibodies A10/8A7 and A10/16E8.
| Antibody | RMSDa,b (Å) | Q-scorea | ||
|---|---|---|---|---|
| Heavy | Light | Heavy | Light | |
| A10/8A7 | 0.48 ± 0.11 | 0.84 ± 0.01 | 0.96 ± 0.02 | 0.92 ± 0.00 |
| A10/16E8 | 0.59 ± 0.13 | 0.71 ± 0.01 | 0.95 ± 0.02 | 0.95 ± 0.00 |
aThe values of RMSD and Q-score were calculated using UCSF Chimera by superimposing the 100 pairs of the top 10 predicted structures of mA10 and each humanized A10 antibody.
bAbbreviation: RMSD, root mean square deviation.