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. Author manuscript; available in PMC: 2023 Jan 1.
Published in final edited form as: J Cyst Fibros. 2021 May 17;21(1):172–180. doi: 10.1016/j.jcf.2021.04.010

Fig. 5. Pathway analysis of differentially expressed proteins within CF ductal epithelia.

Fig. 5.

(A) IPA analysis of disease pathways associated with the differential CF ductal epithelial proteome. (B) IPA analysis of canonical biologic processes and functions associated with the differential CF ductal epithelial proteome. (C) Upstream regulators of the differential CF ductal epithelial proteome related to proinflammatory and redox-dependent signaling pathways. Heatmaps show the Log2(FC) of target molecules of each upstream regulator that were differentially expressed in CF ductal epithelia. (D) Upstream regulators of the differential CF ductal epithelial proteome that are known to influence specification of endocrine cells from ductal progenitors during pancreatic development. Heatmaps show the Log2(FC) of target molecules of each upstream regulator that were differentially expressed in CF ductal epithelia.