Table 2.
Maternal and Infant outcomes among a cohort of 281 pregnant women and 273 infants recruited from September 2015 until July 2019 and followed for one year. Records were not available for eight infants. Women with an STI other than MG who were not co-diagnosed with MG are not shown (n=33). Statistically significant associations at 0.05 are in bold.
| Overall | Mycoplasma Genitalium (may include CT, NG, or TV) | No CT,NG,TV or MG | Unadjusted Difference (Odds Ratio or Mean Difference)† | Adjusted Difference (Odds Ratio or Mean Difference)†† | |||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Maternal | n=281 | n=51 | n=230 | Estimate | 95% CI | Estima | 95% CI |
| Preterm delivery | 21 (8%) | 5 (10%) | 16 (7%) | 1.49 | (0.52, 4.27) | 2.33 | (1.24, 4.37) |
| Spontaneous abortion | 6 (2%) | 0 (0%) | 6 (3%) | 0.00 | - | - | - |
| Endometritis | 2 (1%) | 1 (2%) | 1 (0%) | 4.50 | - | - | - |
| Pelvic inflammatory disease | 1 (0%) | 1 (2%) | 0 (0%) | Inf | (0.11, Inf) | - | - |
| Cervicitis | 1 (0%) | 1 (2%) | 0 (0%) | Inf | (0.11, Inf) | - | - |
| Interim hospitalization | 64 (24%) | 10 (20%) | 54 (24%) | 0.80 | (0.38, 1.71) | 0.74 | (0.47, 1.18) |
| Chorioamnionitis | 13 (5%) | 1 (2%) | 12 (5%) | 0.37 | (0.05, 2.88) | - | - |
| Maternal Fever | 6 (2%) | 1 (2%) | 5 (2%) | 0.93 | - | - | - |
| Length of Stay (days) | 2.6 (1.0) | 2.7 (1.1) | 2.6 (0.9) | 0.10 | (-0.20, 0.39) | 0.02 | (-0.23, 0.28) |
| Gestational age (weeks) | 38.5 (3.8) | 38.5 (2.2) | 38.5 (4.0) | 0.06 | (-1.09, 1.21) | 0.16 | (-0.71, 1.03) |
| Infant | n=273 | n=48 | n=225 | ||||
|
| |||||||
| Low birth weight (< 2500 g) | 22 (8%) | 7 (15%) | 15 (7%) | 2.37 | (0.91, 6.17) | - | - |
| Birth weight (grams) | 3174 (577) | 3012 (543) | 3209 (579) | -197 | (-376.7, -17.5) | -202 | (-345, -59) |
| Sepsis | 0 (0%) | 0 (0%) | 0 (0%) | - | - | - | - |
| ICU stay for infant | 24 (9%) | 4 (8%) | 20 (9%) | 0.93 | (0.30, 2.86) | - | - |
| Apgar (at 1 minute) | 7.6 (1.5) | 7.6 (1.1) | 7.5 (1.6) | 0.09 | (-0.39, 0.57) | 0.25 | (-0.09, 0.58) |
| Apgar (at 5 minutes) | 8.7 (1.1) | 8.6 (1.3) | 8.7 (1.1) | -0.08 | (-0.43, 0.27) | -0.04 | (-0.31, 0.22) |
Difference shown as MG – no STIs or MG relative to no STIs, estimated with the Student’s t test for continuous factors and the Chi-square test for categorical factors, except for factors with one or more category with a frequency below five, where Fisher’s exact test was used.
Adjusted for age, race, education, and risk of STIs using propensity scores. Comparisons with exact statistics are not adjusted.
ICU – Intensive care unit; CT – Chlamydia trachomatis; NG - Neisseria gonorrhoeae; TV – Trichomonas vaginalis; MG – Mycoplasma genitalium.