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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Clin Pharmacol Ther. 2021 Jul 8;110(6):1512–1525. doi: 10.1002/cpt.2320

Figure 4:

Figure 4:

Size of the safety population by quartiles in orphan and non-orphan products and its association to postmarket safety outcome

BW=Boxed Warning; W&P=Warnings and Precautions; C=Contraindications; AR=Adverse Reactions; DI=Drug Interactions