Table 5.
The genes whose expression changes significantly with age in both sexes, and are differentially expressed between lens epithelial cells from aged female mice and male mice.
| SYMBOL | DESCRIPTION | aged vs young FC | aged vs young FDR | young FPKM | aged FPKM | aged female vs male FC | aged female vs male FDR | Male aged FPKM | Female aged FPKM |
|---|---|---|---|---|---|---|---|---|---|
| Cryba1 | crystallin, beta A1 | −3.05 | 3.33E-05 | 1807.54 | 590.89 | 2.33 | 8.08E-03 | 356.79 | 830.56 |
| Crybb1 | crystallin, beta B1 | −2.66 | 1.08E-03 | 769.04 | 288.84 | 2.35 | 1.50E-02 | 173.11 | 407.3 |
| Slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 2.17 | 1.33E-03 | 43.78 | 95.29 | −2.06 | 1.83E-04 | 128.59 | 62.73 |
| Crygs | crystallin, gamma S | −2.39 | 3.03E-03 | 2255.19 | 940.23 | 2.33 | 8.58E-03 | 567.75 | 1321.57 |
| Fabp5 | fatty acid binding protein 5, epidermal | −3.32 | 4.14E-03 | 104.03 | 31.26 | 3.25 | 1.18E-02 | 14.75 | 48.07 |
| Cryba2 | crystallin, beta A2 | −2.01 | 6.83E-03 | 2030.8 | 1011.47 | 2.07 | 4.99E-03 | 661.25 | 1371.15 |
| Crygd | crystallin, gamma D | −85.04 | 1.16E-02 | 119.19 | 1.4 | 60.13 | 2.36E-02 | 0.04 | 2.77 |
| Cryba4 | crystallin, beta A4 | −2.87 | 1.29E-02 | 1087.55 | 378.32 | 3.25 | 5.90E-03 | 178.99 | 581.28 |
| Gpx3 | glutathione peroxidase 3 | 2.66 | 4.68E-02 | 61.17 | 162.73 | −2.36 | 9.69E-05 | 229.28 | 97.36 |
| Matn2 | matrilin 2 | 2.31 | 4.93E-02 | 1.71 | 3.95 | −2.62 | 3.26E-02 | 5.75 | 2.19 |