Figure 1. Graphic comparison of the acute and chronic light models.

In the acute model (A), adult albino fish are dark-adapted for 10 days, subjected to a 30-minute photolesion using the filament light source of a fluorescent microscope (~100,000 lux), followed by continuous light exposure from four 250W halogen lights (~8,000 lux) for four days (Ranski et al., 2018). After 4 days of halogen light exposure, the fish were returned to normal light and dark conditions. The chronic low-light paradigm (B) involved 1 day dark-adaption, no 30 min high-intensity light exposure, and continuous exposure from only two 250W halogen lights (~4000 lux) for 21 days. For both models (C), tissue collection occurred on the same 5 time points post-light onset (0 hr, 18 hpL, 48 hpL, 96 hpL, and 21 dpL).