Table 3.
Associations between baseline fentanyl use and persistence on 1) any medications for opioid use disorder (MOUD) and 2) assigned study MOUD (N = 76 participants initiating MOUD with duration data).
| Mean (sd), Median | IRRa (95% CI); p | Adjusted IRRb (95% CI); p | |
|---|---|---|---|
| Any MOUD | |||
| Fentanyl positive | 3.07 (1.73), 3 | 0.94 (0.70, 1.27); .689 | 0.99 (0.69, 1.42); .953 |
| Fentanyl negative | 3.19 (1.99), 3 | Ref | Ref |
| Assigned study medication | |||
| XR-NTX | |||
| Fentanyl positive | 2.78 (1.86), 2 | 0.82 (0.49, 1.35); .426 | 0.97 (0.48, 1.95); .927 |
| Fentanyl negative | 3.64 (2.21), 4 | Ref | Ref |
| TAUc | |||
| Fentanyl positive | 3.13 (1.75), 3 | 1.23 (0.79, 1.94); .362 | 1.27 (0.78, 2.07); .338 |
| Fentanyl negative | 2.50 (1.56), 2.5 | Ref | Ref |
| Buprenorphine | |||
| Fentanyl positive | 2.71 (1.45), 3 | 1.09 (0.69, 1.75); .702 | 1.17 (0.71, 1.94); .537 |
| Fentanyl negative | 2.50 (1.56), 2.5 | Ref | Ref |
Adjusted for study site only
Adjusted for study site, age, sex, race, ethnicity, severity of substance use, anxiety or depression, and stimulant, benzodiazepine, and other opioid use
Treatment as usual includes buprenorphine or methadone