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p4 is bactericidal ex vivo. Skin biopsies from WT and ChemKO mice were challenged with 1 × 107 CFU of S. aureus 8325-4 in the presence of 100 μM p4 or vehicle (PBS). Data points indicate the CFU of bacteria recovered from the skin surface 24 h after application of bacteria, with each data point representing one cavity and a horizontal line indicating the mean value in each group; n = 5 (1–2 mice per group). **p < 0.01; *p < 0.05 by unpaired t-test.
