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Left arytenoid high-grade neuroendocrine carcinoma, small cell type.
A-C. Hematoxylin-eosin-stained sections at 2x (A), 4x (B), and 10x (C) magnification with salient cytomorphologic features, including nuclear molding, high nuclear/cytoplasm ratio, mitotic activity, apoptosis, and rosetting. D-E. Ancillary studies were supportive of the neuroendocrine phenotype and included immunoperoxidase studies with anti-synaptophysin antibodies (D) and anti-cytokeratin cocktail (E).
