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. 2021 Nov 16;7:357. doi: 10.1038/s41420-021-00750-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — A MHCC-97L cells overexpressed indicated proteins were treated with MG132 (10 μM) for 8 h, and the ubiquitination levels of PTEN protein were investigated. B–E MHCC-97L cells infected with indicated lentiviral plasmids. The cytotoxic effects upon 5-FU (B, C) and oxaliplatin (D, E) were investigated (n = 3).