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. Author manuscript; available in PMC: 2022 May 15.
Published in final edited form as: Clin Cancer Res. 2021 Sep 13;27(22):6174–6183. doi: 10.1158/1078-0432.CCR-21-0987

Table 2.

Association of OX40L positivity with clinicopathologic variables. Statistical analysis by Pearson Chi-Square test.

Variable COHORT 1 (N=280) COHORT 2 (N=207)

OX40L-positive OX40L-negative p-value OX40L-positive OX40L-negative p-value
25 (9%) 255 (91%) 29 (14%) 178 (86%)
Age
   ≤ 70 16 (10%) 152 (90%) 0.719 23 (15%) 127 (85%) 0.420
   > 70 9 (8%) 100 (92%) 4 (10%) 35 (90%)
Gender
   Male 12 (10%) 107 (90%) 0.605 22 (13%) 142 (87%) 0.846
   Female 13 (8%) 144 (92%) 3 (12%) 22 (88%)
Stage
   Stage I-II 21 (10%) 188 (90%) 0.373 14 (13%) 97 (87%) 0.740
   Stage III-IV 4 (6%) 59 (94%) 11 (14%) 66 (86%)
Histology
   ADC 15 (9%) 153 (91%) 0.023 11 (15%) 61 (85%) 0.309
   SCC 8 (15%) 45 (85%) 13 (14%) 78 (86%)
   Others 0 (0%) 49 (100%) 1 (4%) 25 (96%)
Smoking status
   Non/former smoker 9 (6%) 132 (94%) 0.077 1 (6%) 17 (94%) 0.300
   Smoker 16 (13%) 110 (87%) 21 (14%) 125 (86%)