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. Author manuscript; available in PMC: 2022 Nov 15.
Published in final edited form as: Cell Host Microbe. 2021 Oct 11;29(11):1649–1662.e7. doi: 10.1016/j.chom.2021.09.009

Figure 5.

Figure 5.

TM7 alter host bacterial pathogenicity. (A) XH001p was infected with TM7x (red squares) or BB004 (blue triangles), and the subsequent cell density (OD600) was measured across time (passages). (B) 2D alveolar bone loss area analysis from ligature experiment with PBS, XH001p, BB004/XH001 and three XH001np regular colonies (RC). (C) PCR test differences in regular versus irregular colonies (IRC) from established BB004/XH001 coculture. (D) Same infection experiment as in panel A but this time XH001np RC were re-infected with BB004. (E) Quantification of total and small CFUs from experiment in panel B. (B and E) Results are shown as mean (bar) ± SD. Each dot indicates an individual ligature (n = 8-10). N.S., not significant; *p < 0.05, **p < 0.01, ***p < 0.001 by one-way ANOVA followed by Bonferroni post hoc test (B) or Mann-Whitney U test (E).