Skip to main content
. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Otol Neurotol. 2021 Dec 1;42(10):e1410–e1421. doi: 10.1097/MAO.0000000000003356

Figure 2. Distribution of Inner Ear Cell Type Abnormalities Identified in Human Temporal Bone Studies.

Figure 2.

Published temporal bone studies reporting histopathological findings from patients with SSNHL were analyzed to determine the distribution of inner ear cell types found to have structural abnormalities. Graph displays inner ear cell types along the horizontal axis and percentage of abnormal cells on the vertical axis. Cell types include supporting cells (SC), hair cells (HC), stria vascularis (SV), spiral ganglion (SG), tectorial membrane (TM), and spiral limbus (S). Percentage of abnormal cells was calculated by dividing the number of abnormal samples by the total number of analyzed subjects for each cell type. Subjects from studies that did not report findings for particular cell types were excluded from the analysis. Cell type abnormality was defined by criteria that varied by study and included metrics such as significantly decreased cell count and/or presence of structural degeneration or atrophy in SSNHL patient samples compared to controls. Cell type-specific definitions for abnormality are provided in the methods.