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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Contemp Clin Trials. 2021 Sep 29;110:106584. doi: 10.1016/j.cct.2021.106584

Table 1:

Overview of the Five Vignettes Employed in the Vignette Experiment

Vignette type Risk/burden level Vignette details Reasonable amount for an incentive
Notes Low You will keep daily notes of how much water you drink for one week. You will need to make only one clinic visit to go over your notes with a staff member. $10
Notes High You will keep daily notes of drug use and sexual activity for 3 months. You will make a clinic visit each month for 3 months to go over your notes with a staff member. $25/month (total $75)
Drug Low You will take a safe drug once a day for one week. You may have slight dry mouth as a side effect of the drug. $5.00/dose (total $35)
Drug High You will take a safe drug twice a day for a month. You will probably feel very nauseated (sick to your stomach) as a side effect of the drug. $5.00/dose (total $300)
Xray/CT Low You will have one chest x-ray. The amount of radiation from this x-ray is very low. It is same amount of radiation that most people in the country get in 10 days. You will need to make only one clinic visit. $25
Xray/CT High You will receive 3 chest CT-scans. A CT-scan uses a series of x-rays to create pictures of your bones, organs, and other tissues. These 3 scans will expose you to the same amount of radiation that most people in the country get in 5 years. You will have to get the CT scan every 4 months for a year. $55/scan (total $165)
Blood/Muscle Low You will have one tube (3 teaspoons) of blood taken from your arm. You will need to come into the clinic once a month for 3 months to have your blood draw. Like most blood draws, this could cause you a little pain or stress. $25/draw (total $75)
Blood/Muscle High You will have a cut made to get a small amount of muscle tissue from your thigh. This is a very painful procedure that may leave a small scar. You will have to get this done at the clinic each month for 3 months. $100/biopsy (total $300)
Sleep Low You will wear a sleep monitor on your wrist. The monitor fits like a watch. You will have to wear it every night for 30 days. The monitor must be charged every day. $80
Sleep High You will spend the night in a clinic for a sleep study. During the visit, a staff member will attach tubes and wires on top of your skin. This is done so that body activities can be measured while you sleep. You will probably lose several hours of sleep during the visit. $200