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. Author manuscript; available in PMC: 2022 Nov 1.
Published in final edited form as: Contemp Clin Trials. 2021 Sep 29;110:106584. doi: 10.1016/j.cct.2021.106584

Table 4:

Overall Vignette Experiment results

Vignette description (risk/burden level) % would agree to participate Mean price among patient agreeing to participate Mean burden (1=not at all – 5 extremely large) % correctly identified biggest risk of vignette % reporting no risk Mean how bad the specific risk is (1=not at all – 5 extremely bad) Mean likelihood that risk could happen (1=not at all – 5 extremely likely) Mean unpleasant (1=not at all – 5 extremely bad) Most similar common negative event(s) from Anchoring Survey (mean rating)
1a. Spend a night in sleep clinic, get wires attached, lose several hours of sleep (high risk/burden) 82% ns $204 ns 2.16 *** 30% Large loss of sleep 18% 1.87 ns 3.09 *** 1.95 *** Thirsty for an hour (1.91); having a dry mouth (1.81)
1b. Wear a sleep monitor on wrist for 30 days and charge it daily (low risk/burden) 87% $206 1.70 21 % A little loss of sleep 71% 1.76 2.39 1.44 Finger stick for blood by nurse (1.41), getting a flu vaccine injection (1.47)
2a. Take a safe drug twice a day for a month, probably feel very nauseated (high risk/burden) 39% *** $348 ns 2.98 *** 83 % Upset stomach 7% 3.10 *** 3.60 *** 3.13 *** Not being able to get a loan/credit (3.12); Missing an important meeting (3.27)
2b. Take a safe drug daily for a week, may have minor dry mouth as a side effect (low risk/burden) 81% $336 1.68 78 % Dry mouth 16% 1.80 2.63 1.78 Getting bitten by a mosquito, (1.76); being woken before your alarm went off (1.81)
3a. Cut into thigh muscle, very painful and will scar, at clinic monthly for 3 months (high risk/burden) 27% *** $350 ns 3.39 *** 74 % A lot of pain 5% 3.36 *** 3.83 *** 3.46 *** Having severe nausea (3.35); breaking your arm (3.75)
3b. Blood drawn from the arm once a month for 3 months. May have a little pain (low risk/burden) 84% $327 2.04 57 % A little pain 36% 1.56 2.42 1.73 Getting a paper cut (1.73); getting bitten by a mosquito (1.76)
4a. Keep notes of sexual and drug activities for 3 months. Discuss with staff at clinic monthly (high risk/burden) 62% *** $90 p=0.04 2.23 ** 40% Feeling judged or awkward 53% 2.21 *** 2.59 ns 1.89 *** Being thirsty for an hour (1.91); filling out forms for 30 min (1.85)
4b. Keep a daily record of how much water you drink for one week. Discuss with staff at clinic once (low risk/burden) 83% $80 1.91 5% Feeling judged or awkward 90% 1.52 2.13 1.48 Having blood taken by a finger stick by a nurse (1.41), having blood drawn from your arm by a nurse (1.49)
5a. 3 CT Scans every 4 months for one year at clinic. Same radiation as people get in 5 years. (high risk/burden) 50% *** $176 ns 2.51 *** 0.50 Too much radiation 15% 2.86 *** 3.36 *** 2.27 *** Having trouble making a decision (2.26); too many things to do (2.33)
5b. One clinic visit for one chest x-ray. Very low radiation (low risk/burden) 85% $174 1.70 0.58 A little radiation 27% 1.61 2.71 *** 1.47 Having blood taken by a finger stick by a nurse (1.41), having blood drawn from your arm by a nurse (1.49)
Mean, all 5 high risk/burden vignettes 52% *** $209 ns 2.65 NA 20% 2.75 3.38 2.54 Being hungry for a day (2.54); having minor surgery (2.48)
Mean, all 5 low risk/burden vignettes 84% $224 1.81 NA 48% 1.67 2.56 1.58 Feel hot for a brief time (1.69); completing a food diary for a week (1.52)

Note: significance testing compared high and low risk/burden versions of the vignettes

**

p <0.01

***

p<0.001

ns not statistically significant p>0.05; NA not applicable