Figure 5.
VLDL remodeling by the exogenous LpL. (A) Time course of TG lipolysis in group 2 VLDL by bovine LpL (see part 2 Methods for details). The reaction was monitored by quantifying NEFA at indicated time points. (B) Non-denaturing PAGE of VLDL after lipolysis by LpL for indicated times. Band positions corresponding to the particle size of intact VLDL (I), IDL/LDL (II), HDL (III’ and III) and lipid-poor proteins (IV) are indicated. (C) SEC and (D) heparin affinity profiles of VLDL hydrolyzed for indicated times. Peaks I-IV are indicated. The dotted line in D represents the calculated NaCl concentration (100% corresponds to 1.01 M NaCl).