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. Author manuscript; available in PMC: 2022 Aug 25.
Published in final edited form as: Caries Res. 2021 Aug 25;55(5):505–514. doi: 10.1159/000518890

Table 4.

Multivariable models of dental caries in permanent dentition at age 6 years

Variables Unadjusted models Adjusted models
OR 95% CI P OR 95% CI P
Gestational and birth variables
Maternal age at birth 0.901
 <20 years 1.07 (0.34, 3.35) 0.70 (0.18, 2.70) 0.601
 ≥20 years 1.00 1.00
Maternal education 0.004 0.021
 ≤ 8 years 3.80 (1.53, 9.42) 3.68 (1.22, 11.07)
 > 8 years 1.00 1.00
Family income 0.516
 1st tertile 1.79 (0.51, 6.37) 1.11 (0.27, 4.55) 0.886
 2nd tertile 1.95 (0.57, 6.74) 1.61 (0.43, 5.97) 0.475
 3rd tertile 1.00
Weight gestational gain (kg) 1.10 (1.02, 1.17) 0.008 1.08 (1.01, 1.16) 0.029
Child sex 0.765
 Male 1.00 1.00
 Female 1.15 (0.47, 2.80) 1.30 (0.48, 3.54) 0.601
Birth weight 1.00 (1.00, 1.00) 0.564 1.00 (1.00, 1.00) 0.197
Birth height 1.01 (0.84, 1.21) 0.920 0.87 (0.64, 1.17) 0.352
Variables at 6 months
Child BMI z-scores 0.901 0.928
 ≤ 1 SD 1.00 1.00
 > 1 SD 1.06 (0.40, 2.86) 1.05 (0.34, 3.23)
Sugar consumption index 1.33 (1.09, 1.62) 0.005 1.27 (1.02, 1.59) 0.036
Variables at 3 years
Child BMI z-scores 0.922 0.534
 ≤ 1 SD 1.00 1.00
 > 1 SD 1.05 (0.42, 2.63) 0.63 (0.14, 2.74)
Monthly sugar purchase (kg/person) 1.66 (1.14, 2.43) 0.008 1.62 (0.78, 3.36) 0.198
Monthly oil purchase (kg/person) 1.46 (0.84, 2.54) 0.175 0.61 (0.11, 3.42) 0.571
Developmental defects of enamel at 3 years 0.282 0.765
 No 1.00 1.00
 Yes 1.74 (0.63, 4.81) 0.77 (0.15, 4.15)
Visible plaque 0.115 0.590
 No 1.00 1.00
 Yes 2.22 (0.82, 6.01) 1.50 (0.34, 6.63)
Previous dental visit 0.141 0.684
 Yes 1.00 1.00
 No 0.32 (0.07, 1.45) 0.68 (0.11, 4.33)
Dental caries at 3 years 0.001 0.271
 Yes 1.00 1.00
 No 5.30 (1.85, 15.14) 2.26 (0.53, 9.62)

Abbreviations: BMI, body mass index; SD, standard deviation; OR, odds ratio; CI, confidence interval; DMFT, decayed (cavitated or noncavitated), missing due to caries, restored permanent tooth index.

Covariables added to models in serial such that covariables are mutually adjusted for all covariables at the same level or higher (i.e., measured contemporaneously or earlier). All adjusted models also include assignment group in the original trial (intervention or control) as a covariable.