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. Author manuscript; available in PMC: 2022 Dec 1.
Published in final edited form as: Prev Med. 2021 Oct 13;153:106846. doi: 10.1016/j.ypmed.2021.106846

Table 2:

Stratification of Prescription Opioid Use and Long-term Prescription Opioid Use Among Women of Reproductive Age, NHANES 2003-2018

Characteristics Any Opioid Usea (nb=519) vs.
No Opioid Use (n=13,039)
Long-Termc Opioid Use (n=229) vs.
No Opioid Use (n=13,039)
cOR (95% CI)d aOR (95% CI)e cOR (95% CI)d aOR (95% CI)e
Survey Year
2003-2012 Referent Referent
2013-2018 0.62 (0.48-0.80)** 0.59 (0.45-0.78)** 0.85 (0.61-1.19) 0.79 (0.54-1.16)
Age, years
15-24 Referent Referent
25-34 1.46 (1.08-1.95)* 1.32 (0.95-1.85) 2.13(1.19-3.84)* 1.78 (0.95-3.36)
35-44 2.14 (1.64-2.80)** 1.75 (1.27-2.42)** 4.95 (2.98-8.23)** 3.71 (2.08-6.61)**
Race/Ethnicity
Non- Hispanic White Referent Referent
Non-Hispanic Black 0.78 (0.60-1.00) 0.63 (0.48-0.84)** 0.69 (0.49-0.95)* 0.48 (0.33-0.70)**
Hispanic 0.58 (0.44-0.75)** 0.50 (0.37-0.67)** 0.44 (0.29-0.66)** 0.31 (0.19-0.51)**
Non-Hispanic Other 0.45 (0.27-0.74)** 0.46 (0.28-0.76)* 0.71 (0.38-1.30) 0.70 (0.38-1.30)
Pregnant
Yes Referent Referent
No 1.99 (1.04-3.83)* 1.81 (0.94-3.47) 2.60 (0.81-8.40) 1.84 (0.56-6.00)
Missing 0.87 (0.41-1.84) 1.30 (0.60-2.81) 0.52 (0.13-2.16) 1.05 (0.25-4.48)
Education Level
Some High School Referent Referent
High School Diploma 1.30 (0.98-1.72) 1.11 (0.82-1.50) 1.56 (0.99-2.45) 1.26 (0.78-2.06)
More than High School 1.07 (0.85-1.36) 1.05 (0.78-1.40) 1.03 (0.69-1.53) 1.04 (0.64-1.70)
Family Income-to-Poverty Ratio
0.00-1.30 Referent Referent
1.31-1.85 1.06 (0.79-1.41) 1.19 (0.87-1.63) 1.08 (0.65-1.80) 1.40 (0.80-2.46)
1.86-2.50 1.09 (0.73-1.61) 1.17 (0.76-1.79) 1.01 (0.61-1.68) 1.29 (0.72-2.31)
>2.50 0.74 (0.58-0.95)* 0.80 (0.57-1.13) 0.55 (0.37-0.80)** 0.75 (0.45-1.23)
Health Insurance Type
Private Referent Referent
Medicare, Medicaid, or CHIP 1.97 (1.49-2.60)** 1.76 (1.25-2.47)** 3.17 (2.15-4.68)** 2.43 (1.46-4.04)**
Other Insurancef 1.08 (0.76-1.55) 1.07 (0.74-1.54) 1.43 (0.89-2.32) 1.40 (0.83-2.37)
No Insurance 0.80 (0.57-1.11) 0.64 (0.44-0.94)* 0.96 (0.59-1.56) 0.71 (0.42-1.22)
General Health Condition
Excellent, Very Good, or Good Referent Referent
Fair or Poor 3.27 (2.63-4.07)** 3.24 (2.53-4.15)** 6.11 (4.67-8.00)** 5.45 (3.76-7.89)**
Ever Used Heroin g
Yes Referent Referent
No 1.71 (0.71-4.15) 2.38 (0.97-5.86) 2.02 (0.62-6.62) 3.21 (0.96-10.69)
Refused, Don’t know, or Missing 0.79 (0.34-1.84) 1.36 (0.57-3.24) 0.66 (0.21-2.03) 1.49 (0.47-4.72)
a

At least 1 opioid prescription reported as used within the last month. Category includes short-term (<90 days) and long-term use (≥90 days) but does not include MOUD use.

b

Unweighted sample counts

c

At least 1 opioid prescription reported as used for ≥ 90 days and if multiple opioids were reported the longest frequency was used. Participants with long-term use were compared to those with no opioid use (excluded participants with short term opioid use (N=290))

d

Bivariate logistic regressions conducted for each variable separately. Results presented as crude odds ratio (cOR) and 95% wald confidence intervals (95% CI)

e

Multivariate logistic regression adjusted for survey year, age, race, pregnancy status, education level, and income-to-poverty ratio, health insurance type, general health condition, and history of heroin use. Results presented as adjusted odds ratios (aOR) and 95% wald confidence intervals (95% CI)

f

Other insurance includes other types of government insurance and single service plans

g

Respondents answer to question “Have you ever, even once, used heroin?”

Boldface indicates statistical significance

*

p<0.05

**

p<.01