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. 2021 Nov 16;11:22317. doi: 10.1038/s41598-021-01739-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Surgical procedure for implanting specimens into rabbit trochlear grooves. (a) The right knee of each rabbit was shaved and sterilized with povidone–iodine. (b) In the supine position, the right legs were incised longitudinally from 2 cm above the knee joint to 1.5 cm below. (c) A hole with a 6 mm trephine burr was created on the proximal side of the trochlear groove. (d) A specimen was placed in the hole with the porous surface facing the cancellous bone. (e) The specimen was gently impacted to facilitate contact with the cancellous bone. (f) Patella reduction was performed and the incision was repaired.