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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Prev Med. 2021 Aug 19;153:106766. doi: 10.1016/j.ypmed.2021.106766

Table 3.

Self-Reported Adverse Respiratory Symptoms by Frequency of E-Cigarette Use

Connecticut Adolescents Northern California Adolescents Southern California Young Adults: CHS1 Southern California Young Adults: HH2
%3 AOR4 (95% CI) %3 AOR4 (95% CI) %3 AOR4 (95% CI) %3 AOR4 (95% CI)
Outcome: Bronchitis 5,6
E-cigarette use categories:7
 Never used e-cigarettes 21.4 reference 26.0 reference 20.1 reference 14.2 reference
 Ever used but 0 days in past 30 days 21.7 1.01 (0.83, 1.22) 28.9 1.11 (0.77, 1.60) 26.6 1.21 (0.90, 1.62) 17.0 1.02 (0.75, 1.39)
 1–5 days in past 30 days 23.7 1.13 (0.91, 1.40) 32.9 1.14 (0.79, 1.65) 33.8 1.25 (0.70, 2.23) 15.9 0.89 (0.54, 1.45)
 6–30 days in past 30 days 30.0 1.57 (1.30, 1.89) 43.0 1.52 (1.22, 1.90) 42.5 2.07 (1.23, 3.49) 23.2 1.34 (0.89, 2.01)
Outcome: Asthma 5,6
E-cigarette use categories:7
 Never used e-cigarettes 16.3 reference 17.3 reference 14.7 reference 14.6 reference
 Ever used but 0 days in past 30 days 15.0 0.90 (0.72, 1.12) 20.5 1.15 (0.73, 1.82) 16.0 0.92 (0.66, 1.30) 18.1 1.17 (0.86, 1.58)
 1–5 days in past 30 days 20.1 1.27 (1.01, 1.59) 17.0 0.76 (0.48, 1.17) 32.5 1.78 (0.96, 3.28) 25.2 1.67 (1.09, 2.57)
 6–30 days in past 30 days 26.7 1.85 (1.52, 2.26) 22.5 0.98 (0.59, 1.64) 27.9 1.61 (0.89, 2.93) 18.5 1.04 (0.68, 1.58)
Outcome: Shortness of breath 5,6
E-cigarette use categories:7
 Never used e-cigarettes 17.9 reference 19.4 reference 15.2 reference 18.2 reference
 Ever used but 0 days in past 30 days 19.9 1.10 (0.90, 1.35) 17.3 0.81 (0.57, 1.14) 18.9 1.24 (0.90, 1.73) 22.7 1.15 (0.87, 1.52)
 1–5 days in past 30 days 22.4 1.23 (0.98, 1.53) 18.0 0.77 (0.45, 1.32) 23.4 1.92 (0.99, 3.73) 26.3 1.56 (1.02, 2.40)
 6–30 days in past 30 days 28.5 1.87 (1.53, 2.28) 35.9 1.88 (1.37, 2.59) 11.5 0.89 (0.41, 1.92) 22.7 1.42 (0.95, 2.11)
1.

Children’s Health Study

2.

Happiness and Health Study

3.

Prevalence of the respiratory outcome in each e-cigarette use category

4.

Odds ratios from logistic regression models adjusted for gender, race/ethnicity, school lunch program participation (adolescents), personal income (young adults), age, past 30-day combustible tobacco, past 30-day use of cannabis. Missing covariable values multiply imputed for California samples.

5.

Composite outcome, including ≥1 symptom (see: Table 2)

6.

Bold text in table cells indicates statistically significant (P<0.05) difference in odds of the respiratory outcome compared to reference, calculated separately for each study

7.

Based on number of days used the most-frequently used e-cigarette device type

Abbreviations: AOR = adjusted odds ratio; CI = confidence interval